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KMID : 0380619990310041096
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Korean Journal of Food Science and Technology
1999 Volume.31 No. 4 p.1096 ~ p.1100
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The Protective Effect of Bifidobacterium breve K - 110 , K - 111 and B . infantis K - 525 on Carbon Tetrachloride - induced Hepatotoxicity in Rats
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Choi Eung-Chil
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Abstract
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The protective effect of Bifidobacterium breve K-110, K-111 and B. infantis K-525 on carbon tetrachlorideinduced hepatotoxicity in rats was investigated. Among them, B. infantis K-525 had the most potent hepatoprotective activity. It reduced serum aspartate aminotransferase and alanine aminotransferase levels to 51% and 80% of the CCl₄-treated groups, respectively. In rat liver homogenate intoxificated with CCl₄, B. infantis K525 inhibited in vitro as well as in vivo lipid peroxidation more than the other Bifidobacteria.
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